What would be the appx costs of a boiler exchange for my gas central heating ?

I have a 3 bed semi with an annexe built on with a room and en suite wet room complete with electric shower, I also need a new double panel radiator, room thermostat and thermo valves fitted to 5 radiators.The boiler would be fitted in the airing cupboard, I would prefer a good quality combi boiler, I understand that Worcester boilers are one of the better makes, also the old back boiler would need disconnecting. There are 7 radiators in the house. Mike